iTOF® Device
&
iTOF®App
The world’s first FDA-cleared wireless, app-controlled TOF monitor is now fully
automated and AI-assisted
iTOF 2.0 delivers unmatched precision, safety, and efficiency
from induction to reversal for
state-of-the-art quantitative neuromuscular blockade management
Get iTOF 2.0 for iOS
Install the FREE APP
Go to the settings menu and select Get Started, view videos or start the Demo Mode to use a virtual iTOF device.
Get iTOF 2.0 for Android
Install the FREE APP
Go to the settings menu and select Get Started, view videos or start the Demo Mode to use a virtual iTOF device.
iTOF User Manual
The iTOF consists of a quantitative neuromuscular transmission monitoring app (software) and a Bluetooth connected nerve stimulation device (hardware).
Nerbio iTOF Specifications
iTOF Product Hardware & Software Specifications: (± 2 %) as well as International Safety and Efficacy Compliance Certifications.
A New Generation of NMB Monitoring
Nerbio’s new iTOF App 2.0 revolutionizes monitoring with start-to-finish automation with smart data analysis tools that allow for seamless integration into your perioperative workflow:
✔ Graphically displays depth of paralytic block for easy management of case progression
✔ True Start-to-Finish Automation – Automatically selects optimal test mode and intervals for TOF%, TOF Count, and PTC monitoring throughout the perioperative period.
✔ Automatically signals adequate reversal for safe extubation
✔ Automatically sets key parameters for type of patient and drugs used.
✔ Optional “on/off” PTC twitch for monitoring of prolonged deep block
✔ Easily customize monitoring to align with the anesthesiologist’s case-by-case management of intubation and extubation.
Nerbio iTOF 2.0 — Smarter Monitoring, Faster Recovery
The FDA-cleared iTOF 2.0 delivers fully automated, AI-assisted monitoring from induction through reversal—optimizing dosing, improving safety, and streamlining workflow in every case.
Engineered for precision, mobility, and security—at a lower total cost—iTOF 2.0 helps transform operating rooms into intelligent, connected care environments.
Powered by the Nerbio iCARE™ Platform, it integrates modular wireless sensors, AI guidance, and mobile connectivity.
Try iTOF 2.0 now with the built-in Demo Mode. No device required.
The New iTOF 2.0 — Designed for Smarter Monitoring
True Start-to-Finish Automation –selects optimal test mode and intervals for TOF%, TOF Count, and PTC throughout perioperative period.
Wirelessly monitor patients through the Nerbio App - Maintains solid wireless connections to one or more iTOF devices for up to 40 ft. with Bluetooth.
Complete case setup data can quickly be entered on a single screen, including patient and drug particulars.
Intensity, timing and other key parameter settings are always accessible from the main screen for easy control.
Paused cases can be resumed by anyone - with all settings, case data and history restored ensuring operational efficiency.
With AI - powered voice & text guidance, interactive training videos, and instant support.
FHIR-Enabled Wireless Monitoring
Real-Time Data. Universal Connectivity.
Nerbio’s FHIR-enabled wireless platform connects patients, clinicians, and hospital systems in real time — transforming how vital data flows across the OR and ICU.
With direct FHIR + HL7 integration, live physiologic data streams securely from Nerbio devices straight into existing hospital displays and electronic records — no middleware, no manual charting, no lag.
Nerbio’s Portal provides HIPAA Compliant real-time data for PreOp, OR and PACU management and tracks drug usage for verification of service value.
For Clinicians: Mobile, cable-free monitoring means freedom at the bedside and instant visibility on every connected screen.
For Hospitals: Seamless EMR integration, automated documentation, and future-proof interoperability built on FDA-cleared, HIPAA-secure architecture.
Why Clinicians Choose iTOF 2.0
iTOF 2.0 sets a new standard with patented accuracy, AI assistance, and
seamless workflow integration — ensuring continuous,
guided neuromuscular block assessment from induction to recovery
Optimized Recovery
Precise monitoring improves antagonist timing and reduces residual paralysis risk.
Faster Patient Throughput
Portable and wireless, moving seamlessly from Pre-Op to OR to PACU.
Personalized Management
Easy setup checklist customizes parameters for each patient and drug type.
Integrated Case History
Real-time interactive plots and complete records for compliance and review.
Enhanced Safety
Quantitative, guideline-compliant monitoring supports safe extubation.
Built-in AI assistance
Voice & text guidance, interactive training videos, and instant support.
The next generation of neuromuscular monitoring
Download Nerbio iTOF 2.0
iTOF 2.0 isn’t just an upgrade — it’s a step change in neuromuscular monitoring, giving clinicians smarter automation, cleaner workflow, and safer outcomes in every procedure.