FOR IMMEDIATE RELEASE
San Jose, CA — 05/__/2025 — Nerbio, a global innovator in mobile-based anesthesia and critical care monitoring solutions, today released results from a multi-center case study highlighting the successful clinical adoption of its flagship device, the iTOF®, in over 1,700 surgical cases across India. The study confirms that iTOF—an FDA-cleared, app-controlled neuromuscular monitoring device—is not only clinically effective but highly accepted by anesthesia professionals, overcoming one of the key barriers to widespread adoption of quantitative monitoring in surgery.
Key Findings Include:
“iTOF is an innovative, user-friendly AI-enabled device,” said Dr. Sandeep Mutha of Poona Hospital. “Its ability to calculate supramaximal current, utilize multiple monitoring modes, and deliver AI-driven guidance makes it highly efficient in daily practice.”
The case study, which tracked device usage across 16 anesthesiologists and 1,771 surgical procedures, focused on adoption behavior, workflow integration, and decision-making around neuromuscular blockade (NMB) management—a critical element of modern anesthesia practice. The findings underscore iTOF’s intuitive design, mobile connectivity, and clinical reliability, all of which contributed to rapid uptake by practitioners who previously relied on qualitative, often inaccurate assessments.
Addressing a Global Clinical Need
Leading anesthesia societies including the ASA (American Society of Anesthesiologists) and ESAIC (European Society of Anaesthesiology and Intensive Care) have long called for universal adoption of quantitative twitch monitoring to reduce the risks associated with incomplete reversal of neuromuscular blockade. However, uptake has lagged due to workflow disruption concerns, complexity of traditional systems, and resistance to change in fast-paced clinical environments.
iTOF answers this challenge with:
Disrupting the Legacy Model
The study reinforces Nerbio’s broader mission: to disrupt the traditional medical equipment model by offering compact, software-driven tools that are smarter, more affordable, and easier to implement. Unlike legacy twitch monitors that require large capital purchases, the iTOF can be deployed flexibly across perioperative teams, democratizing access to gold-standard monitoring and significantly reducing capital and operating costs for hospitals.
“This is a powerful example of how advanced, wireless app-enabled technology can improve both patient safety and hospital efficiency,” said Dr. Henry Sullivant, CEO of Nerbio and former VP & Chief Medical Officer at Baptist Memorial Health Care Corporation. “Ease of use and clinical impact don’t need to be mutually exclusive—we believe iTOF proves both are possible.”
Looking Ahead
With its Memphis-based U.S. sales operations now underway, Nerbio plans to further expand its clinical footprint across North America. Future development efforts are already in progress for other intelligent monitoring tools—covering areas such as brain activity, respiratory monitoring, and noninvasive blood pressure—each aimed at transforming the way hospitals deliver care.
To learn more about the study or request full clinical data, contact Nerbio below or see the whitepaper here: https://nerbio.com/our-vision/
Media Contact:
Ken Leonard
Chief Innovation Officer
media@nerbio.com
About Nerbio:
Nerbio is a medical technology company that is revolutionizing critical care monitoring through the development of compact, wireless app-controlled devices utilizing advanced sensor technology, AI-powered assistance and intelligent mobile connectivity. With its international headquarters in San Jose, CA, and U.S. sales operations based in Memphis, TN, Nerbio is dedicated to transforming the delivery of critical care worldwide.
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